8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 1 Development of Complex Curricula for Molecular Bionics and Infobionics Programs within a consortial* framework** Consortium leader PETER PAZMANY CATHOLIC UNIVERSITY Consortium members SEMMELWEIS UNIVERSITY, DIALOG CAMPUS PUBLISHER The Project has been realised with the support of the European Union and has been co-financed by the European Social Fund *** **Molekuláris bionika és Infobionika Szakok tananyagának komplex fejlesztése konzorciumi keretben ***A projekt az Európai Unió támogatásával, az Európai Szociális Alap társfinanszírozásával valósul meg. PETER PAZMANY CATHOLIC UNIVERSITY SEMMELWEIS UNIVERSITY sote_logo.jpg dk_fejlec.gif INFOBLOKK 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 2 Peter Pazmany Catholic University Faculty of Information Technology BASICS OF NEUROBIOLOGY ORGANIZATIONOF THE BRAIN STEM www.itk.ppke.hu Neurobiológia alapjai (Agytörzs szerkezete) ZSOLT LIPOSITS Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 3 www.itk.ppke.hu SPINO-MEDULLARY JUNCTION. PYRAMIDAL DECUSSATION 1. Nucleus gracilis 1 2. Nucleus cuneatus 2 3 3. N. spinalis n.V 5 5. Tr. spinocerebellaris d. 6. Tr. spinothalamicus 6 7 7. Tr. spinocerebellaris v. 8. Decussatio pyramidum 8 9 9. Pyramid 10 10. Nucleus n.XII 11 11. Nucleus ambiguus. N. motorius IX,X,XI Lemniscus medialis RubberBrainstemBack 4 4. Tr. spinalis n.V Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 4 www.itk.ppke.hu MEDULLA OBLONGATA LEVEL OF DECUSSATION OF THE MEDIAL LEMNISCUS Fibrae arcuatae Lemniscus medialis Decussatio lemniscorum Tr. corticospinalis Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 5 www.itk.ppke.hu MEDULLA AT LEVEL OF THE INFERIOR OLIVE RubberBrainstemBack 1. N. nervi XII 2. N. dorsalis. n. X 3. N. et tractus solitarius 5. Ped. cerebellaris inf. 4. N. ambiguus 6. Lemniscus medialis 7. Oliva inferior 1 2 3 5 4 6 7 8 8. Tr. corticospinalis Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 6 www.itk.ppke.hu THE OPEN PART OF THE MEDULLA 5. N. cochlearis dorsalis 5 6. N. cochlearis ventralis 6 7. Oliva inferior 7 9. Lemniscus medialis 9 10. Basis pontis 10 11. Pedunculus cerebellaris medius 11 1. N. vestibularis medialis 1 2. N. vestibularis inferior 2 3. N. et tr. spinalis n. V 3 4. Ped. cerebellaris inf. 4 8. Pyramidal tract 8 Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 7 10 10. Nuclei pontis www.itk.ppke.hu PONS AT THE LEVEL OF THE FACIAL COLLICULUS 1 1. Colliculus facialis 2 2. Brachium pontis 3 3. Corpus trapezoideum 4 4. Lemniscus medialis 5 5. Oliva superior 7 7. Lemniscus lateralis 8 8. Pontocerebellar fibers 9 9. Pyramidtract 6. N. motorius n. VII 6 RubberBrainstemBack Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 8 www.itk.ppke.hu PONS AT THE LEVEL OF TRIGEMINAL NUCLEI 1. BRACHIUM PONTIS 2. N. TRIGEMINUS 3. LM+ EDINGERTRACT (E) 4. LEMN. LATERALIS 5. N. MOT. N. V 6. N. SEN. PRINC. N. V. 7. PYRAMID TRACT 1 2 3 4 5 6 7 8 8. 4THVENTRICLE RubberBrainstemBack Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 9 www.itk.ppke.hu ROSTRAL PART OF THE PONS 1 1. 4THVENTRICLE 2 2. UPPERCEREBELLAR PEDUNCLE 3 3. CEREBELLUM 4 4. BRACHIUM PONTIS 5 5. FASC. LONG. MED. 7 6 6. LM+E 7. LEMNISCUS LATERALIS 8 8. PYRAMID TRACT (TR. CORTICOPONTINUS, TR, CORTICOBULBARIS, TR.CORTICOSPINALIS) Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 10 www.itk.ppke.hu MESENCEPHALON AT THE LEVEL OF INFERIOR COLLICULI 1. AQUEDUCTUS CEREBRI 1 2 2. COLLICULUS INFERIOR 3 3. LEMNISCUS LATERALIS 4 4. NUCL. NERVI IV. 5 5. DECUSSATIONOF CEREBEL. PED. 6 6. LM+E 7 7. SUBSTANTIA NIGRA 8 8. PEDUNCULUS CEREBRI 9 9. N. OCULOMOTORIUS 10 10. CENTRAL GRAY MATTER RubberBrainstemBack Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 11 www.itk.ppke.hu MESENCEPHALON AT THE LEVEL OF SUPERIOR COLLICULI 1 1. COLLICULUS SUPERIOR 2 2. NUCLEUS RUBER 3 3. NUCLEUS N. III. 4 4. LM+E 5 5. SUBSTANTIANIGRA 6 6. TR. FRONTOPONTINUS 7 7. TR. CORTICOBULBARIS ET SPINALIS 8 8. TR. OCCIPITO-TEMPOROPONTINUS RubberBrainstemBack Basics of Neurobiology: Organization of the brain stem 8/8/2011. TÁMOP –4.1.2-08/2/A/KMR-2009-0006 12 www.itk.ppke.hu THE RETICULAR FORMATION OF THE BRAIN STEM MAIN REGULATORY FUNCTIONS RESPIRATION CIRCULATION FEEDING EYE MOVEMENTS MOTOR COORDINATION STATE OF CONSCIOUSNESS AROUSAL